Synergistic effect of Microbicidal Materials

Ana Maria Montagut

Nowadays, surface contamination by microbes is a universal challenge in medical, domestic, and industrial settings. For that reason it is important the creation of new microbicidal materials in order to solve this problem.

Silver nanoparticles are well known for their properties against a wide range of bacteria, viruses, and fungi. Owing to their characteristics they are now one of the most commercialized nanomaterials having applications in over 200 products such as antimicrobial coatings, medical devices, molecular diagnostics and photonic devices, sensors, textiles, home water purifiers, household appliances…1

Due to the development of antibiotic resistance by different kind of bacteria, the pharmaceutical industry and scientists are focused on the research of new non-classic antibacterial agents.2

Accordingly, in the present work new silver nanoparticles have been prepared using as a ligand different antibiotics, such as eugenol, triarylmethanes and fluoroquinolones, in order to find a synergistic effect between the ligand and the nanoparticle. All of these nanoparticles have been fully characterized and have been microbicidally tasted, giving excellent results against both S. Aureus and Pseudomona.



  1. Singh, R.;Shedbalkar, U. U.;Wadhwani, S. A.; Chopade, B. A. Appl Microbiol     Biotechnol. 2015, 4579-93.
  2. Vignoni, M.; Weerasekera, H. A.; Simpson, M. J.; Phopase, J.; Mah, T. F.; Griffith, M.; Alarcon, E. I.; Scaiano, J. Nanoscale 2014, 6, 5725 –5728 /